Keep in mind that the benefit of fat grafting is that the material is natural, comes from your own body and has the potential of lasting for several to many years.  The disadvantage however, is that in a small percentage of people fat grafts applied to the lips, cheeks or face disappear without leaving a lasting benefit. An alternative for lip enlargement or lip augmentation is the injection of Juvederm Ultra filler to enlarge the lips.  This injection consists of hyaluronic acid a natural component of the body that lasts for approximately 6 months.  This is done during an office visit or consultation and is a non-surgical treatment.